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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=29589
Proper Citation: RRID:MMRRC_029589-UCD
Description: Mus musculus with name B6.129P2(D2)-Tnfrsf9tm1Byk/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Immunology and Inflammation, Virology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: cortical renal glomerulopathies [MP:0000523]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| skin lesions [MP:0001212]| abnormal lacrimal gland morphology [MP:0001346]| decreased IgM level [MP:0001806]| premature death [MP:0002083]| abnormal kidney morphology [MP:0002135]| abnormal outer ear morphology [MP:0002177]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| increased IgA level [MP:0002495]| increased anti-nuclear antigen antibody level [MP:0004794]| increased susceptibility to systemic lupus erythematosus [MP:0004801]| abnormal class switch recombination [MP:0004816]| increased B-1 B cell number [MP:0004977]| abnormal cytotoxic T cell physiology [MP:0005078]| increased double-negative T cell number [MP:0005090]| increased T cell proliferation [MP:0005348]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| abnormal common myeloid progenitor cell morphology [MP:0006410]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008206]| increased B-2 B cell number [MP:0008481]| increased spleen germinal center number [MP:0008495]| decreased IgG1 level [MP:0008496]| decreased IgG2a level [MP:0008498]| decreased IgG3 level [MP:0008500]| increased IgG2a level [MP:0008501]| increased IgG2b level [MP:0008567]| decreased interferon-gamma secretion [MP:0008664]| decreased interleukin-12 secretion [MP:0008688]| decreased interleukin-2 secretion [MP:0008699]| increased interleukin-4 secretion [MP:0008700]| decreased interleukin-4 secretion [MP:0008880]| lacrimal gland inflammation [MP:0009335]| decreased splenocyte proliferation [MP:0009336]| increased splenocyte proliferation [MP:0013452]| increased lacrimal gland apoptosis [MP:0020518]
Affected Gene: Tnfrsf9
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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