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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15109
Proper Citation: RRID:MMRRC_015109-UCD
Description: Mus musculus with name B6;129-Lamb2tm1Jrs/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Developmental Biology, Internal/Organ, Metabolism, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal retinal photoreceptor morphology [MP:0001004]| abnormal retinal rod cell morphology [MP:0001005]| abnormal neuromuscular synapse morphology [MP:0001053]| failure of neuromuscular synapse presynaptic differentiation [MP:0001054]| failure of neuromuscular synapse postsynaptic differentiation [MP:0001055]| abnormal retina morphology [MP:0001325]| postnatal growth retardation [MP:0001732]| glomerulonephritis [MP:0002743]| albuminuria [MP:0002871]| increased urine protein level [MP:0002962]| abnormal retinal outer plexiform layer morphology [MP:0003732]| abnormal synaptic vesicle clustering [MP:0004793]| abnormal miniature endplate potential [MP:0004835]| lethargy [MP:0005202]| abnormal amacrine cell morphology [MP:0005240]| abnormal eye physiology [MP:0005253]| abnormal Muller cell morphology [MP:0005547]| abnormal eye electrophysiology [MP:0005551]| decreased amacrine cell number [MP:0008106]| fused podocyte foot processes [MP:0008139]| short photoreceptor inner segment [MP:0008582]| short photoreceptor outer segment [MP:0008587]| abnormal retinal development [MP:0009772]| abnormal retina inner limiting membrane morphology [MP:0010235]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011348]| abnormal renal glomerulus basement membrane morphology [MP:0011409]| increased renal glomerulus basement membrane thickness [MP:0011856]| abnormal glomerular filtration barrier function [MP:0011965]| decreased total retina thickness [MP:0030005]
Affected Gene: Lamb2
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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