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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=10570
Proper Citation: RRID:MMRRC_010570-UNC
Description: Mus musculus with name B6;129S5-Slc26a5tm1Jnz/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection:
Phenotype: organ of Corti degeneration [MP:0000043]| decreased body weight [MP:0001262]| deafness [MP:0001967]| cochlear ganglion degeneration [MP:0002857]| cochlear hair cell degeneration [MP:0004362]| cochlear inner hair cell degeneration [MP:0004398]| abnormal cochlear outer hair cell morphology [MP:0004399]| cochlear outer hair cell degeneration [MP:0004404]| absent cochlear microphonics [MP:0004413]| decreased cochlear microphonics [MP:0004414]| decreased cochlear nerve compound action potential [MP:0004417]| abnormal Claudius cell morphology [MP:0004430]| absent cochlear outer hair cell electromotility [MP:0004436]| decreased cochlear outer hair cell electromotility [MP:0004437]| degeneration of organ of Corti supporting cells [MP:0004465]| short cochlear outer hair cells [MP:0004466]| abnormal distortion product otoacoustic emission [MP:0004736]| absent distortion product otoacoustic emissions [MP:0004737]| increased cochlear nerve compound action potential [MP:0004767]| impaired hearing [MP:0006325]| abnormal otoacoustic response [MP:0006336]| increased or absent threshold for auditory brainstem response [MP:0011967]
Affected Gene: Slc26a5
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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