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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=10461
Proper Citation: RRID:MMRRC_010461-UCD
Description: Mus musculus with name B6;129-Erbb4tm1Grl/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cardiovascular, Developmental Biology, Internal/Organ, Models for Human Disease, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal blood flow velocity [MP:0000233]| absent trabeculae carneae [MP:0000296]| decreased atrioventricular cushion size [MP:0000301]| increased granulocyte number [MP:0000322]| abnormal mammary gland development [MP:0000628]| abnormal cerebellar granule layer morphology [MP:0000886]| abnormal motor neuron innervation pattern [MP:0000940]| abnormal sensory neuron innervation pattern [MP:0000968]| abnormal cranial nerve morphology [MP:0001056]| abnormal trigeminal nerve morphology [MP:0001065]| abnormal facial nerve morphology [MP:0001071]| abnormal vestibulocochlear nerve morphology [MP:0001072]| abnormal glossopharyngeal nerve morphology [MP:0001073]| abnormal cranial ganglia morphology [MP:0001081]| abnormal geniculate ganglion morphology [MP:0001082]| abnormal trigeminal ganglion morphology [MP:0001092]| thick pulmonary interalveolar septum [MP:0001179]| decreased anxiety-related response [MP:0001364]| hyperactivity [MP:0001399]| lung inflammation [MP:0001861]| increased airway responsiveness [MP:0001952]| abnormal long term potentiation [MP:0002207]| abnormal pulmonary alveolar duct morphology [MP:0002271]| abnormal respiratory function [MP:0002327]| enhanced long term potentiation [MP:0003008]| abnormal prepulse inhibition [MP:0003088]| abnormal vestibulocochlear ganglion morphology [MP:0003703]| abnormal surfactant secretion [MP:0004780]| decreased pulmonary respiratory rate [MP:0005574]| impaired lung alveolus development [MP:0006027]| abnormal mammary gland growth during pregnancy [MP:0006269]| decreased prepulse inhibition [MP:0009142]| impaired contextual conditioning behavior [MP:0009454]| impaired cued conditioning behavior [MP:0009456]| abnormal mammary gland alveolus morphology [MP:0009506]| perinatal lethality [MP:0011090]| incomplete penetrance [MP:0011098]| embryonic lethality during organogenesis [MP:0012757]| complete penetrance [MP:0013716]
Affected Gene: Erbb4
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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