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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=413
Proper Citation: RRID:MMRRC_000413-UCD
Description: Mus musculus with name B6.129X1-Prkar1atm1Gsm/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Reproduction; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal cell morphology [MP:0000358]| abnormal foregut morphology [MP:0000474]| abnormal somite shape [MP:0001691]| abnormal embryo size [MP:0001697]| decreased embryo size [MP:0001698]| pericardial edema [MP:0001787]| reduced male fertility [MP:0001922]| increased tumor incidence [MP:0002020]| increased sarcoma incidence [MP:0002032]| abnormal developmental patterning [MP:0002084]| abnormal embryonic tissue morphology [MP:0002085]| abnormal primitive streak morphology [MP:0002231]| enhanced wound healing [MP:0002724]| increased hepatocellular carcinoma incidence [MP:0003331]| increased hemangiosarcoma incidence [MP:0003667]| decreased heart rate variability [MP:0003929]| embryonic growth retardation [MP:0003984]| failure of initiation of embryo turning [MP:0004180]| increased fibrosarcoma incidence [MP:0010363]| embryonic lethality during organogenesis [MP:0011098]| complete penetrance [MP:0011205]| excessive folding of visceral yolk sac [MP:0011732]| decreased somite size [MP:0012081]| absent heart tube [MP:0012183]| decreased paraxial mesoderm size [MP:0012272]| decreased axial mesoderm size [MP:0012498]
Affected Gene: Prkar1a
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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