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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=413
Proper Citation: RRID:MMRRC_000413-UCD
Description: Mus musculus with name B6.129X1-Prkar1atm1Gsm/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Reproduction; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal cell morphology [MP:0000358]| abnormal foregut morphology [MP:0000474]| abnormal somite shape [MP:0001691]| abnormal embryo size [MP:0001697]| decreased embryo size [MP:0001698]| pericardial edema [MP:0001787]| reduced male fertility [MP:0001922]| increased tumor incidence [MP:0002020]| increased sarcoma incidence [MP:0002032]| abnormal developmental patterning [MP:0002084]| abnormal embryonic tissue morphology [MP:0002085]| abnormal primitive streak morphology [MP:0002231]| enhanced wound healing [MP:0002724]| increased hepatocellular carcinoma incidence [MP:0003331]| increased hemangiosarcoma incidence [MP:0003667]| decreased heart rate variability [MP:0003929]| embryonic growth retardation [MP:0003984]| failure of initiation of embryo turning [MP:0004180]| increased fibrosarcoma incidence [MP:0010363]| embryonic lethality during organogenesis [MP:0011098]| complete penetrance [MP:0011205]| excessive folding of visceral yolk sac [MP:0011732]| decreased somite size [MP:0012081]| absent heart tube [MP:0012183]| decreased paraxial mesoderm size [MP:0012272]| decreased axial mesoderm size [MP:0012498]
Affected Gene: Prkar1a
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)