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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=367
Proper Citation: RRID:MMRRC_000367-UCD
Description: Mus musculus with name B6;129S4-Neurod1tm1Jle/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cell Biology, Developmental Biology, Diabetes, Endocrine Deficiency, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection: BCBC-Beta Cell Biology Consortium
Phenotype: absent dentate gyrus [MP:0000814]| small cerebellum [MP:0000852]| abnormal cerebellar foliation [MP:0000857]| thin external granule cell layer [MP:0000873]| abnormal Purkinje cell morphology [MP:0000877]| decreased Purkinje cell number [MP:0000880]| abnormal cerebellar granule layer morphology [MP:0000886]| decreased sensory neuron number [MP:0000966]| abnormal sensory neuron innervation pattern [MP:0000968]| decreased body weight [MP:0001262]| decreased retinal photoreceptor cell number [MP:0001327]| abnormal optic nerve morphology [MP:0001330]| ataxia [MP:0001393]| abnormal motor coordination/balance [MP:0001516]| impaired balance [MP:0001525]| hyperglycemia [MP:0001559]| postnatal growth retardation [MP:0001732]| deafness [MP:0001967]| abnormal vestibular ganglion morphology [MP:0002856]| increased retinal ganglion cell number [MP:0002983]| absent cochlear ganglion [MP:0003146]| abnormal cochlear sensory epithelium morphology [MP:0003308]| reduced modiolus [MP:0003310]| abnormal vestibulocochlear ganglion morphology [MP:0003703]| abnormal retinal layer morphology [MP:0003727]| abnormal retinal photoreceptor layer morphology [MP:0003728]| abnormal retinal outer nuclear layer morphology [MP:0003731]| abnormal retinal inner nuclear layer morphology [MP:0003733]| absent endocochlear potential [MP:0004410]| abnormal amacrine cell morphology [MP:0005240]| abnormal retinal ganglion layer morphology [MP:0005241]| abnormal Muller cell morphology [MP:0005547]| abnormal horizontal cell morphology [MP:0006068]| abnormal retinal neuronal layer morphology [MP:0006069]| abnormal retinal apoptosis [MP:0006072]| abnormal retinal bipolar cell morphology [MP:0006073]| absent amacrine cells [MP:0006095]| decreased retinal ganglion cell number [MP:0006309]| decreased amacrine cell number [MP:0008106]| decreased retinal cone cell number [MP:0008446]| thin retinal inner nuclear layer [MP:0008511]| disorganized retinal outer nuclear layer [MP:0008516]| abnormal neuron differentiation [MP:0009937]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011089]| perinatal lethality [MP:0030005]
Affected Gene: Neurod1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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