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Organism Name

B6.129-Eya1^tm1Rilm/Mmucd

RRID:MMRRC_000361-UCD RRID Copied

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RRID:MMRRC_000361-UCD

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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=361

Proper Citation: RRID:MMRRC_000361-UCD

Description: Mus musculus with name B6.129-Eya1^tm1Rilm/Mmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: Developmental Biology; Mutation Type: Targeted Mutation ; Collection:

Phenotype: abnormal inner ear morphology [MP:0000026]| abnormal cochlea morphology [MP:0000031]| abnormal lateral semicircular canal morphology [MP:0000037]| absent endolymphatic duct [MP:0000041]| absent premaxilla [MP:0000090]| abnormal basisphenoid bone morphology [MP:0000106]| rib fusion [MP:0000154]| double outlet right ventricle [MP:0000284]| decreased cell proliferation [MP:0000352]| microcephaly [MP:0000433]| abnormal cranium morphology [MP:0000438]| abnormal jaw morphology [MP:0000454]| mandible hypoplasia [MP:0000460]| abnormal pulmonary artery morphology [MP:0000484]| absent kidney [MP:0000520]| absent parathyroid glands [MP:0000680]| athymia [MP:0000705]| abnormal skeletal muscle morphology [MP:0000759]| abnormal facial nerve morphology [MP:0001071]| abnormal vestibulocochlear nerve morphology [MP:0001072]| abnormal geniculate ganglion morphology [MP:0001082]| absent petrosal ganglion [MP:0001086]| eyelids open at birth [MP:0001302]| abnormal thyroid cartilage morphology [MP:0002260]| abnormal semicircular canal morphology [MP:0002428]| persistent truncus arteriosis [MP:0002633]| pituitary gland hypoplasia [MP:0002659]| cochlear ganglion degeneration [MP:0002857]| abnormal posterior semicircular canal morphology [MP:0002858]| abnormal cardiovascular development [MP:0002925]| abnormal hyoid bone morphology [MP:0003056]| absent malleus processus brevis [MP:0003110]| anotia [MP:0003142]| absent cochlea [MP:0003147]| decreased cochlear coiling [MP:0003148]| absent lateral semicircular canal [MP:0003161]| decreased lateral semicircular canal size [MP:0003162]| absent posterior semicircular canal [MP:0003163]| decreased posterior semicircular canal size [MP:0003164]| decreased superior semicircular canal size [MP:0003166]| renal hypoplasia [MP:0003446]| thyroid hypoplasia [MP:0003499]| single kidney [MP:0003604]| small lung [MP:0003641]| absent ureter [MP:0003722]| fusion of middle ear ossicles [MP:0003740]| abnormal craniofacial development [MP:0003935]| abnormal aortic arch morphology [MP:0004113]| interrupted aortic arch [MP:0004157]| right aortic arch [MP:0004158]| retroesophageal right subclavian artery [MP:0004160]| absent stapes [MP:0004204]| abnormal epaxial muscle morphology [MP:0004248]| absent vestibular ganglion [MP:0004299]| small otic vesicle [MP:0004310]| absent inner ear vestibule [MP:0004314]| absent vestibular saccule [MP:0004315]| small vestibular saccule [MP:0004317]| decreased vestibular hair cell number [MP:0004328]| increased cochlear inner hair cell number [MP:0004395]| abnormal vestibular labyrinth morphology [MP:0004427]| abnormal pterygoid process morphology [MP:0004452]| abnormal pubis morphology [MP:0004506]| abnormal ischium morphology [MP:0004507]| abnormal orientation of cochlear hair cell stereociliary bundles [MP:0004522]| decreased outer hair cell stereocilia number [MP:0004529]| absent maxilla [MP:0004539]| cervical vertebral fusion [MP:0004620]| conductive hearing loss [MP:0004739]| impaired branching involved in ureteric bud morphogenesis [MP:0004936]| abnormal cell differentiation [MP:0005076]| abnormal middle ear ossicle morphology [MP:0005105]| abnormal incus morphology [MP:0005106]| abnormal stapes morphology [MP:0005107]| abnormal extraocular muscle morphology [MP:0005247]| abnormal zygomatic bone morphology [MP:0005270]| abnormal temporal bone morphology [MP:0005272]| small cranium [MP:0005352]| small pituitary gland [MP:0005361]| absent outer ear [MP:0005579]| abnormal endolymphatic duct morphology [MP:0006011]| abnormal tympanic membrane morphology [MP:0006018]| decreased tympanic ring size [MP:0006020]| abnormal otic vesicle development [MP:0006030]| abnormal ureteric bud morphology [MP:0006032]| abnormal external auditory canal morphology [MP:0006033]| increased apoptosis [MP:0006042]| abnormal vestibular saccule morphology [MP:0006089]| abnormal utricle morphology [MP:0006090]| abnormal cardiac outflow tract development [MP:0006126]| absent hypaxial muscle [MP:0006284]| absent inner ear [MP:0006285]| abnormal lung epithelium morphology [MP:0006382]| increased otic epithelial cell apoptosis [MP:0008063]| decreased otic epithelial cell proliferation [MP:0008064]| short endolymphatic duct [MP:0008065]| abnormal sternocostal joint morphology [MP:0008148]| abnormal semicircular canal ampulla morphology [MP:0008488]| abnormal palate development [MP:0009653]| absent external auditory canal [MP:0009707]| abnormal mitotic spindle morphology [MP:0009760]| cleft secondary palate [MP:0009890]| decreased palatine bone horizontal plate size [MP:0009895]| decreased maxillary shelf size [MP:0009897]| abnormal hyoid bone lesser horn morphology [MP:0009914]| vascular ring [MP:0010466]| absent ureteric bud [MP:0010978]| neonatal lethality [MP:0011087]| complete penetrance [MP:0011386]| increased metanephric mesenchyme apoptosis [MP:0011967]| increased or absent threshold for auditory brainstem response [MP:0012729]| abnormal common carotid artery morphology [MP:0013163]| absent thyroid gland isthmus [MP:0013222]| abnormal first pharyngeal pouch morphology [MP:0013290]| persistent ultimobranchial bodies [MP:0030097]| preauricular pit [MP:0030155]| absent tympanic cavity [MP:0030161]| absent auditory bulla [MP:0030204]| large nasal septum [MP:0030421]| tongue muscle hypoplasia [MP:0030426]

Affected Gene: Eya1

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Catalog Number: 000361-UCD

Background: Targeted Mutation

Database: Mutant Mouse Resource and Research Center (MMRRC)

Database Abbreviation: MMRRC

Source References: PMID:10471511

Alternate IDs: MMRRC_361-UCD, MMRRC_000361, MMRRC_361

Organism Name: B6.129-Eya1^tm1Rilm/Mmucd

Record Creation Time: 2023-03-07 09:47:52

Record Last Update: 2026-08-08 05:31:08

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)

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