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URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=204
Proper Citation: RRID:MMRRC_000204-UNC
Description: Mus musculus with name B6.129X1-Wrntm1Lgu/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal adipose tissue distribution [MP:0000013]| fragile skeleton [MP:0000061]| osteoporosis [MP:0000066]| decreased compact bone thickness [MP:0000135]| kyphosis [MP:0000160]| alopecia [MP:0000414]| abnormal crypts of Lieberkuhn morphology [MP:0000490]| abnormal femur morphology [MP:0000559]| small gonad [MP:0001116]| small testis [MP:0001147]| decreased body weight [MP:0001262]| cataract [MP:0001304]| abnormal skeleton physiology [MP:0001533]| hyperglycemia [MP:0001559]| impaired wound healing [MP:0001792]| increased sarcoma incidence [MP:0002032]| increased circulating insulin level [MP:0002079]| premature death [MP:0002083]| abnormal bone marrow morphology [MP:0002397]| delayed wound healing [MP:0002908]| abnormal telomere length [MP:0003155]| abnormal chromosome morphology [MP:0003702]| premature aging [MP:0003786]| increased osteosarcoma incidence [MP:0003789]| abnormal compact bone morphology [MP:0003797]| increased osteoclast cell number [MP:0004984]| impaired glucose tolerance [MP:0005293]| abnormal cell physiology [MP:0005621]| abnormal bone ossification [MP:0008271]| decreased subcutaneous adipose tissue amount [MP:0008844]| decreased trabecular bone thickness [MP:0009346]| abnormal bone trabecula morphology [MP:0010867]| decreased bone trabecula number [MP:0010869]| decreased trabecular bone mass [MP:0010873]| decreased bone volume [MP:0010876]| abnormal osteoid morphology [MP:0010924]| decreased compact bone area [MP:0010968]| increased bone trabecular spacing [MP:0013630]
Affected Gene: Wrn
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
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