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Proper Citation: RRID:MGI:5829277
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased circulating aspartate transaminase level, increased liver cholesterol level, increased circulating LDL cholesterol level, increased retroperitoneal fat pad weight, increased gonadal fat pad weight, increased body weight, oxidative stress, increased hepatocyte apoptosis, decreased fatty acid oxidation, abnormal mitochondrial ATP synthesis coupled electron transport, gallstones, decreased oxygen consumption, liver inflammation, decreased bile salt level, abnormal bile salt homeostasis, abnormal bile composition, increased circulating triglyceride level, increased bile salt level, increased circulating alanine transaminase level, increased circulating bilirubin level, jaundice, increased subcutaneous adipose tissue amount, increased sensitivity to induced morbidity/mortality, increased susceptibility to diet-induced obesity, increased susceptibility to atherosclerosis, abnormal lipid level, abnormal protein level, decreased circulating HDL cholesterol level, increased circulating cholesterol level, increased white fat cell size, decreased liver triglyceride level, decreased circulating triglyceride level, decreased circulating free fatty acid level, increased white fat cell lipid droplet size, mortality/aging
Affected Gene: Pon3
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Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI
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