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Proper Citation: RRID:MGI:5829028
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased glucagon secretion, abnormal pancreatic alpha cell differentiation, abnormal pancreatic alpha cell morphology, premature death, pancreatic islet hyperplasia, increased circulating insulin level, enlarged pancreatic islets, increased pancreas tumor incidence, increased pancreatic ductal adenocarcinoma incidence, increased pancreatic islet cell adenoma incidence, improved glucose tolerance, decreased circulating glucagon level, increased pancreatic alpha cell number, dilated renal tubules, increased glucagonoma incidence
Affected Gene: Pcsk2
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Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI
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