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Proper Citation: RRID:MGI:5691952
Description: Allele Detail: Targeted, Transgenic This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted, Transgenic This is a legacy resource.
Phenotype: hepatic necrosis, increased collagen level, increased fatty acid level, hepatic steatosis, decreased liver cholesterol level, increased liver weight, increased circulating phospholipid level, increased circulating free fatty acid level, increased circulating cholesterol level, decreased circulating LDL cholesterol level, increased circulating bilirubin level, increased circulating aspartate transaminase level, increased circulating alanine transaminase level, abnormal circulating lipoprotein level, weight loss, abnormal liver physiology, abnormal liver parenchyma morphology, premature death, increased circulating LDL cholesterol level, abnormal circulating apolipoprotein level, postnatal lethality, incomplete penetrance, hypoglycemia, increased unsaturated fatty acid level, jaundice, increased liver triglyceride level, decreased circulating triglyceride level, enlarged liver, decreased circulating cholesterol level, pale liver, liver failure
Affected Gene: Hmgcr
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No rating or validation information has been found for Tg(Alb1-cre)1Dlr; Hmgcrtm2Ishi/Hmgcrtm2Ishi.
No alerts have been found for Tg(Alb1-cre)1Dlr; Hmgcrtm2Ishi/Hmgcrtm2Ishi.
Source: MGI
Source Database: MGI, Mouse Genome Informatics MGI
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