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Proper Citation: RRID:MGI:5575759
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: decreased spleen red pulp amount, decreased leukocyte cell number, increased cell proliferation, increased bone marrow cell number, decreased lymphocyte cell number, thrombocytopenia, polychromatophilia, postnatal lethality, incomplete penetrance, neonatal lethality, incomplete penetrance, lethality throughout fetal growth and development, incomplete penetrance, myeloid hyperplasia, premature death, increased single-positive T cell number, increased monocyte cell number, impaired hematopoiesis, increased apoptosis, abnormal common myeloid progenitor cell morphology, spleen atrophy, increased number of Howell-Jolly bodies, abnormal megakaryocyte morphology, abnormal neutrophil morphology, abnormal spleen white pulp morphology, small spleen, decreased spleen weight, anemia, anophthalmia, abnormal hematopoietic stem cell physiology, abnormal leukocyte morphology, decreased B cell number, decreased body size, decreased hematopoietic stem cell number, decreased body weight, decreased erythroid progenitor cell number
Affected Gene: Asxl1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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