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Proper Citation: RRID:MGI:3664612
Description: Allele Detail: Targeted, Transgenic This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted, Transgenic This is a legacy resource.
Phenotype: abnormal intestinal goblet cell morphology, enlarged spleen, spleen hyperplasia, abnormal spleen morphology, abnormal intestine morphology, absent regulatory T cells, decreased T cell number, abnormal colon morphology, decreased T cell proliferation, decreased CD4-positive, alpha beta T cell number, abnormal T cell activation, decreased CD8-positive, alpha-beta T cell number, decreased single-positive T cell number, increased memory T cell number, enlarged lymph nodes, weight loss, rectal prolapse, colitis, intestinal ulcer, chronic diarrhea
Affected Gene: Map3k7
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No rating or validation information has been found for Tg(Lck-cre)1Jtak; Map3k7tm1Aki/Map3k7tm1Aki.
No alerts have been found for Tg(Lck-cre)1Jtak; Map3k7tm1Aki/Map3k7tm1Aki.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI