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Beth Israel Deaconess Medical Center Functional Genomics and Bioinformatics Core Facility (RRID:SCR_024877)Copy Citation Copied
URL: https://www.baderc.org/cores/functional-genomics-and-bioinformatics-core/
Proper Citation: Beth Israel Deaconess Medical Center Functional Genomics and Bioinformatics Core Facility (RRID:SCR_024877)
Description: Core provides consultative, laboratory, and bioinformatic services for next generation sequencing based applications.Core services include Pre- and post-experimental consultation to determine proper experimental approach, design, and interpretation; Standalone RNA preparation, RNA and DNA Bioanalyzer analyses, chromatin shearing/shear checks; Sample quality assessment of DNA and RNA using the BioAnalyzer and Qubit assays; Library preparation, sequencing, and analysis of transcriptomes (RNA-seq), cistromes (ChIP-seq), chromatin accessibility (ATAC-seq); Standalone sequencing on NextSeq500; Multiplexed 10x Single Cell/Nucleus Library RNA-seq Droplet generation, Library Preparation; Basic data analysis: quality assessment and normalization, genomic alignment, differential expression/enrichment, functional enrichment analysis (overrepresentation and GSEA), sample clustering, and motif enrichment; Bespoke data analysis, including integration of complex ChIP-seq and RNA-seq data sets, single-cell sequencing analyses.Core is located on the 7th floor of the Center for Life Sciences building in the Longwood Medical area (3 Blackfan Circle, CLS-728).
Synonyms: Functional Genomics and Bioinformatics Core
Resource Type: access service resource, core facility, service resource
Keywords: ABRF, next generation sequencing services, RNA, DNA, chromatin shearing, library preparation; basic data analysis,
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