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URL: http://ccb.jhu.edu/software/tophat/index.shtml
Proper Citation: TopHat (RRID:SCR_013035)
Description: Software tool for fast and high throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies. Fast splice junction mapper for RNA-Seq reads. Aligns RNA-Seq reads to mammalian-sized genomes using ultra high-throughput short read aligner Bowtie, and then analyzes mapping results to identify splice junctions between exons.TopHat2 is accurate alignment of transcriptomes in presence of insertions, deletions and gene fusions.
Synonyms: tophat, TopHat1, Tophat2
Resource Type: data processing software, sequence analysis software, software resource, data analysis software, image analysis software, alignment software, software application
Defining Citation: PMID:23618408, PMID:19289445, DOI:10.1093/bioinformatics/btp120
Keywords: align, RNA-Seq, read, cDNA, sequencing, transcriptomics, fast, splice, junction, mapper, exon, analysis, bio.tools
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