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MGH High Resolution Peripheral Quantitative Computed Tomography Core Facility (RRID:SCR_009924)Copy Citation Copied
URL: http://harvard.eagle-i.net/i/0000013b-3d48-24a1-e81d-064c80000000
Proper Citation: MGH High Resolution Peripheral Quantitative Computed Tomography Core Facility (RRID:SCR_009924)
Description: Core facility that provides the following services: 3D Imaging, Normative data comparison, Scan review. The High Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) Core Facility offers measurements of the microscopic internal structure of cortical and trabecular bone in the distal radius and tibia. Additionally, the HR-pQCT Core Facility offers Finite Element Analysis to estimate key biomechanical properties of the bone including failure load and stiffness. By scanning the distal radius and tibia, the HR-pQCT Core can measure a variety of important parameters reflecting the integrity or cortical and trabecular bone. This information cannot be determined using standard clinical imaging techniques such as dual-energy x-ray absorptiometry (DXA). A scanning appointment is a 30 minute addition to a clinical research visit and involves less radiation exposure than traditional bone densitometry. With applications for both cross-sectional and longitudinal research, investigators have employed our facilities and expertise to study a variety of bone-related diseases with participants ranging in age from children to the elderly. The goal of the HR-pQCT Core is to provide facilities and personnel on a per study basis, allowing investigators access to important information about bone structure and function without requiring special expertise and equipment. Getting Started: To begin organizing a cohort for HR-pQCT studies or to inquire further, please contact the Core Director, Dr. Joel Finkelstein.
Resource Type: service resource, access service resource, core facility
Keywords: imaging technique, dual energy x-ray absorptiometry, data analysis, quality control
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