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URL: http://www.neuro.mpg.de/borst

Proper Citation: Max Planck Institute of Neurobiology: Systems and Computational Neurobiology (RRID:SCR_008048)

Description: Department devoted to the study of how motion information from retinal images is computed in the fly visual system and how this information is decoded for flight control. In general, this processing is done in two steps: In the first step, local motion vectors are calculated from local changes in retinal brightness. This calculation is done according to the InternReichardt model of local motion detection, most likely in the fly''s medulla. From the resulting vector fields (the neural optic flow), important course control parameters are extracted in a second step. This department''s work combines experimental and theoretical analysis ranging from visual responses, membrane properties and pharmacology of individual neurons up to network responses to natural image sequences created by the flys own flight maneuvers. The experimental animals used are the blow fly Calliphora vicina (InternBigFly) and the fruitfly Drosophila melanogaster (InternLittleFly). While the first species allows for intracellular and optical recording from individual neurons, the latter provides in addition a wealth of genetic techniques including tissue specific expression of genetically encoded indicators and blockers of nervous activity. Experimental,Theoretical, Analysis, Membrane, Property, Pharmacology, Neuron, Network, Natural, Animal, Blow fly, Cappiphora vicina, Fruitfly, Drosophila melanogaster, Specie, Intracellular, Genetic, Technique, Tissue, Expression, Indicator, Nervous, Activity In collaboration with Winfried Denk (MPI for Medical Research, Heidelberg), this resource also try to fully reconstruct important parts of the optic lobes of both species at the ultrastructural level using his recently developed Serial Block Face Scanning Electron Microscope (InternBlueFly). Biophysically realistic compartmental models of individual neurons obtained from 2P-image stacks allow us to reconstitute the network of motion processing neurons in computer simulations (InternModelFly). As a joint project with Martin Bussand Kolja Kuehnlenz, the knowledge about the fly motion vision system goes into the development of miniature airborne vehicles (InternRoboFly). T

Synonyms: MPI S&C Neurobiology

Resource Type: data or information resource, portal, department portal, organization portal

Keywords: drosophila melanogaster, experimental, expression, flight control, fly, fruitfly, genetic, activity in collaboration with winfried denk (mpi for medical research, analysis, animal, blow fly, brightness, cappiphora vicina, computed, heidelberg), indicator, intracellular, medulla, membrane, motion, natural, nervous, network, neural optic flow, neuron, pharmacology, property, retinal, specie, technique, the knowledge about the fly motion vision system goes into the development of miniature airborne vehicles (internrobofly). t, theoretical, this resource also try to fully reconstruct important parts of the optic lobes of both species at the ultrastructural level using his recently developed serial block face scanning electron microscope (internbluefly). biophysically realistic compartmental models of individual neurons obtained from 2p-image stacks allow us to reconstitute the network of motion processing neurons in computer simulations (internmodelfly). as a joint project with martin bussand kolja kuehnlenz, tissue, vector, visual system, image