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URL: http://www.ebi.ac.uk/thornton-srv/databases/archschema/
Proper Citation: ArchSchema (RRID:SCR_004947)
Description: ArchSchema is a java webstart application that generates dynamic plots of related Pfam domain architectures. The protein sequences having each architecture can be displayed on the plot and separately listed. Where there is 3D structural information in the PDB, the relevant PDB codes can be shown on the plot. Sequences can be be filtered by organism, or the output can be limited to just those protein sequences for which there is structural information in the PDB. Search by UniProt sequence id, or by Pfam domain id. Red underlines indicate the extent to which 3D structures of the domains and architectures are available in the PDB. Left-clicking on a node shows a panel containing information about the constituent domains, the protein sequences having the given architecture, and any sequences that have whole or partial structures in the PDB. You can display protein sequence (or, alternatively, the protein structures) associated with each architecture. You can download ArchSchema to run locally from your own machine. Note, however, you only download the code and not the data. Thus you will need to be connected to the Internet whenever you perform a search from within ArchSchema. The search initiates a call to the EBI which returns the data to ArchSchema for graphing.
Abbreviations: ArchSchema
Synonyms: ArchSchema - graphs of related Pfam domain architectures
Resource Type: production service resource, source code, software resource, data analysis service, service resource, analysis service resource, software application
Defining Citation: PMID:20299327
Keywords: gold standard
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