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URL: http://discover.nci.nih.gov/gominer/GoCommandWebInterface.jsp
Proper Citation: High-Throughput GoMiner (RRID:SCR_000173)
Description: A web program that organizes lists of genes of interest (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology and automates the analysis of multiple microarrays then integrates the results across all of them in exportable output files and visualizations. High-Throughput GoMiner is an enhancement of GoMiner and is implemented with both a command line interface and a web interface. The program can also: efficiently perform automated batch processing of an arbitrary number of microarrays; produce a human- or computer-readable report that rank-orders the multiple microarray results according to the number of significant GO categories; integrate the multiple microarray results by providing organized, global clustered image map visualizations of the relationships of significant GO categories; provide a fast form of false discovery rate multiple comparisons calculation; and provide annotations and visualizations for relating transcription factor binding sites to genes and GO categories.
Resource Type: software resource, web application
Defining Citation: PMID:15998470
Keywords: term enrichment, gene ontology, gene, microarray, common variable immune deficiency, high-throughput, visualization, database
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